Digestive Disease Week  ·  May 2–5, 2026  ·  Chicago, IL Pancreas Club  ·  May 2–3, 2026  ·  Swissôtel Chicago

Bringing Clarity to
Elevated Pancreatic Cancer Risk

Visit ClearNote Health at DDW 2026 to see how the Avantect® Pancreatic Cancer Test is transforming early detection for high-risk individuals.

Booth #2248  ·  West Hall  ·  McCormick Place

Avantect

We hope to see you in Chicago.

ClearNote Health will be presenting new clinical data for the Avantect® Pancreatic Cancer Test at DDW 2026 — including two scientific presentations featuring validation data from our multiomics liquid biopsy platform for high-risk surveillance.

Visit us at Booth #2248 (West Hall) to speak with the team about early detection and how Avantect is changing the conversation around elevated pancreatic cancer risk.

The Avantect® Pancreatic Cancer Test

Featured at DDW 2026
When pancreatic cancer risk is elevated, clarity matters.

The Avantect® Pancreatic Cancer Test is a multiomics blood-based assay integrating epigenomic 5-hydroxymethylcytosine (5hmC) patterns, genomic features from cfDNA, and glycan biomarker measurements within an optimised machine-learning algorithm — delivering a single actionable result for individuals at elevated risk.

82.6%
Overall sensitivity
(95% CI: 77.4%–87.0%)
76.8%
Stage I/II sensitivity
(95% CI: 68.9%–83.6%)
97.5%
Specificity
(95% CI: 96.4%–98.3%)

Clinically validated in a case-control study of pancreatic cancer patients (n=259) and non-cancer subjects (n=1,186).

Designed for patients at elevated risk

Certain clinical and inherited factors are associated with significantly elevated pancreatic cancer risk. The Avantect Pancreatic Cancer Test is designed for individuals with one or more of the following:

Family History
of pancreatic cancer
Relative Risk: 4 – Over 9x1,2,3
Genetic Predisposition
BRCA1, BRCA2, ATM, MLH1, MSH2, MSH6, EPCAM, CKDN2A, PRSS1, SPINK1, STK11/LKB1
Relative Risk: 2.3 – Over 30x2
New-onset Diabetes
in adults over age 50
Relative Risk: 6 – 8x4,5,6
Discover More

Scientific Presentations

ClearNote Health research will be presented in two sessions at DDW 2026.

Plenary Presentation
Evaluation of Blood-Based Molecular Biomarker Test for the Surveillance of Individuals at High Risk for Pancreatic Cancer
PresenterAnna BergamaschiPhD, Vice President, Product Development, ClearNote Health
Date & Time3 May 2026  ·  3:49 PM CST
LocationASGE Presidential Plenary – Innovation, Education, Practice, Prevention – Past, Present and Future
Poster Presentation
Evaluation of a Blood-Based Molecular Biomarker Test for the Surveillance of Individuals at High Risk for Pancreatic Cancer
PresenterRandall BrandMD, Director, UPMC GI Malignancy Early Detection, Diagnosis and Prevention Program; Professor of Medicine, University of Pittsburgh School of Medicine
Date & Time4 May 2026  ·  12:50 PM CST
LocationPoster Hall, Level 3, Hall F2, McCormick Place

Meet the Team at Booth #2248

Our team will be available throughout the conference for meetings and conversations.

Anna Bergamaschi
Anna Bergamaschi
VP, Product Development
Sam Levy
Sam Levy
Chief Science Officer
Jeff Venstrom
Jeff Venstrom
Chief Medical Officer
Michele Merritt
Michele Merritt
Strategic Accounts Director, West
Jeremy Bennett
Jeremy Bennett
Head of Marketing
Vince Furci
Vince Furci
Sr. Director, National Strategic Accounts

Avantect Resources

Download the latest clinical evidence and product information for the Avantect® Pancreatic Cancer Test.

Avantect® Pancreatic Cancer Test
Multiomics Early Detection of Pancreatic Cancer

Learn how Avantect® integrates 5hmC epigenomics, genomic cfDNA features, and glycan biomarkers within a machine-learning algorithm to deliver high sensitivity and specificity for early-stage pancreatic cancer detection.

↓  Download Whitepaper
Avantect® Physician Brochure
Actionable Insights for Elevated-Risk Pancreatic Cancer Care

A concise overview for clinicians covering risk factor criteria, clinical performance data, ordering workflow, and result interpretation to support next-step decisions in elevated-risk care.

↓  Download Brochure

References

  1. Klein AP. Genetic susceptibility to pancreatic cancer. Mol Carcinog 2012;51:14–24.
  2. NCCN. Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic Version 3.2025.
  3. Aslanian HR, Lee JH, Canto MI. AGA Clinical Practice Update on Pancreas Cancer Screening in High-Risk Individuals: Expert Review. Gastroenterology 2020;159:358–62.
  4. Chari ST, Leibson CL, Rabe KG, et al. Pancreatic cancer-associated diabetes mellitus: prevalence and temporal association with diagnosis of cancer. Gastroenterology 2008;134:95–101.
  5. Chari ST, Wu B, Lopez C, et al. Risk of Pancreatic Cancer in Glycemically Defined New-Onset Diabetes: A Prospective Cohort Study. Gastroenterology 2025.
  6. Sharma A, Kandlakunta H, Nagpal SJS, et al. Model to Determine Risk of Pancreatic Cancer in Patients With New-Onset Diabetes. Gastroenterology 2018;155:730–9 e3.

Connect with Us at DDW 2026

Visit us at Booth #2248 (West Hall). Book time with our team in advance to make the most of your conference schedule.

Schedule a Meeting

Important Information

The Avantect Pancreatic Cancer Test is an early detection test. The test does not establish a diagnosis of pancreatic cancer, and results should be considered in the context of other clinical criteria. A definitive diagnosis of cancer is rendered by clinical providers through a combined use of diagnostic testing, imaging, biopsy, and pathological findings. Not all pancreatic cancers will be detected. Some patients with pancreatic cancer may have a "Signal not detected" result. Some patients without pancreatic cancer may have a "Signal detected" result. False-negative and false-positive results are possible. A "Signal not detected" result does not guarantee that no pancreatic cancer is present. In some cases, no result is obtained. While this is very uncommon, it may be caused by shipping delays or when there is not enough cell-free DNA for the test in the patient's blood. If this happens, additional blood samples may be required to produce a patient result.

The Avantect Pancreatic Cancer Test was developed in the ClearNote Health CLIA-certified (CLIA# 05D2249973) and CAP-accredited (CAP# 9219174) laboratory and has not been cleared or approved by the US Food and Drug Administration (FDA). ClearNote Health, Inc., 10578 Science Center Drive #210, San Diego, CA 92121. Tel +1 833 258-7827.